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Pending positive outcomes from ongoing and forthcoming RCTs, GLP-1 RA medications may become a pharmacotherapeutic approach for treating polysubstance use. Alcohol Addiction Among all substances, alcohol is by far the most investigated when it comes to GLP-1 RAs

The reduction in plasma glucose enhances insulin sensitivity and -cell function

The overall heterogeneity for MACE was low (I 2 = 15.3%, 95% uncertainty intervals, 0 and 52.3%) (Table S3)

But by using a root-cause lens and focusing on natural remedies, many patients see significant improvements and healing

In that situation, D50W might be preferable (e.g., one 50-ml ampule of D50W every six hours)

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