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The relationship between dose and effect was close to linear across the studied range
All subjects were started on GLP-1 analog monotherapy, and 22.9% were initiated on the add-on treatment (bupropion/naltrexone)
this is consistent with a protective effect of GLP-1 RAs on both short and long time-scales
But the reductions were specific to insulin, a product under intense congressional and public scrutiny, and did not represent a general strategic shift
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