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In addition to the deleterious effects of hyperglycemia, studies proved that diabetic patients exhibit an impaired response to intestinal hormones called incretins compared to individuals with normal blood glucose level
By inhibiting pro-inflammatory cytokines and signaling pathways, these compounds can reduce OS induced by inflammation
Access this article Similar content being viewed by others References Papers of particular interest, published recently, have been highlighted as: Of importance Marras C, Beck JC, Bower JH, Roberts E, Ritz B, Ross GW, et al
However, a recent 12-week multicenter study comparing the efficacy of GLA (320 mg/day) and ALA (600 mg/day) in participants with T2D and painful DPN found that after 12 weeks, both neuropathic symptoms and pain improved, and GLA was shown to be non-inferior (equally effective) to ALA in reducing pain intensity [115]
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Lower Risk of Serious Metabolic Disease Excess weight puts significant strain on the liver, heart, hormones, and joints
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