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Recommended Dosing The starting dose of hydroxocobalamin for adults is 5 g administered as an intravenous infusion over 15 minutes (approximately 15 mL/min)
Long-Term Safety Considerations: While safety data from clinical trials spanning up to 24 weeks is reassuring, long-term safety data spanning years of continuous use remains limited
The neutralization capacity of 3G10 and 5C6 was first assessed using pseudovirus neutralization assays
Acute symptoms such as fatigue may improve within days, whilst neurological symptoms like paraesthesia typically require weeks to months of treatment
Both medications represent major advances over previous pharmaceutical options
No drawn-out timelines
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