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Underlying Health Conditions: Individuals with gastrointestinal issues, autoimmune disorders, or neurological conditions may need longer to feel the full benefits

Pregnant or breastfeeding individuals should consult their healthcare provider to determine the most appropriate treatment plan

Any of these warrant a protocol reassessment and potentially a conversation with a healthcare provider

This is why gut dysfunction is linked to depression and anxiety even in patients with no obvious digestive symptoms

10.3389/fmicb.2021.780768 Front Microbiol

If you are concerned about getting every last unit out of a vial, they are worth the small extra investment