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doi:10.1097/MED.0000000000000660

The DAC modification significantly extends its half-life, allowing for prolonged activity and making it ideal for studies on muscle growth, recovery, anti-aging, and fat metabolism

This makes retatrutide a high-interest subject for studies involving non-alcoholic fatty liver disease (NAFLD) and metabolic-associated steatotic liver disease (MASLD), where glucagon activity is highly relevant

A medicine is not judged only by weight loss

Tirzepatide at 10 and 15 mg significantly reduced HbA1c levels and body weight compared to semaglutide 2 mg, with greater reductions of -0.36% and -0.4% in HbA1c, and -3.15 kg and -5.15 kg in body weight, respectively

(PubMed) Curhan GC, Willett WC, Rimm EB, Stampfer MJ