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Avoid with prior pancreatitis or semaglutide hypersensitivity
Its structural backbone derives from a modified Gastric Inhibitory Polypeptide sequence
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Older adults (60+) or those with obesity, metabolic syndrome, or poor baseline health may start at 250-300mcg given their typically reduced pituitary sensitivity and response
Additionally, ensuring adequate rest and managing stress through meditation, deep breathing, or relaxation techniques can make nausea less pronounced
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