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We typically recommend a 24 week break after 812 weeks on for chronic protocols the necessity isn't fully established, but it's a sensible conservative approach for long-term use

And although studies have shown it reduces initial body weight at a lower rate than other GLP-1s, its still an effective weight loss treatment that could end up saving you money

Retatrutide, with its additional glucagon pathway, may theoretically have different tolerance characteristics

Its effectiveness also extends to improved insulin secretion and reduced glucagon levels

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Mounjaro contains tirzepatide and activates two receptor systems: GIP and GLP-1