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The primary outcomes assessed included the one-repetition maximum (1RM) strength, indicators of muscle hypertrophy (as measured by DXA, CT, and biopsy), and rates of MPS (utilizing deuterated water as a tracer)

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Likewise, the Womens Health Initiative calcium plus vitamin D (CaD) trial reported no overall reduction in breast cancer incidence but observed a modest reduction in ductal carcinoma in situ (DCIS), suggesting potential long-term preventive effects under sustained supplementation (315)

Obesity (Silver Spring) 2021;29:802820

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Side effects were more common in the oral semaglutide group (16.7%) than in the injection group (4.9%)