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Glutathione functions through two primary mechanisms: direct scavenging of reactive oxygen species (ROS) and serving as a cofactor for glutathione peroxidase, a family of enzymes that neutralize hydrogen peroxide and lipid peroxides [2][4]

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Amplite Fluorimetric Glutathione GSH/GSSG Ratio Assay Kit Green Fluorescence When cells are exposed to increased levels of oxidative stress, GSSG will accumulate and the ratio of GSH to GSSG will decrease

Cell-derived EVs can deliver regulatory RNAs, proteins, lipids, and mitochondrial components to recipient cells [27,28,29,30]