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Avoid initial stimulants
Worsening of diabetic retinopathy has been observed primarily with semaglutide during rapid glycemic improvement, particularly in patients with pre-existing retinopathy
If tolerance is good and no adverse effects occur, increase to 75mg daily, often split into two doses of approximately 37.5mg each
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These issues can include blurred vision, worsening diabetic retinopathy, and problems related to the optic nerve
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