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Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
Adequate protein intake is the single most important preventive measure
The clinical job is making sure those few weeks don't derail the patient
Concurrent Medications and Safety Considerations: Concomitant use of other antihyperglycemic agents, particularly insulin or sulfonylureas, may influence the apparent speed of glycemic improvement and necessitate dose adjustments to prevent hypoglycemia
The phased introduction protocol is especially important with tirzepatide
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