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Severe side effects are rare for both but require medical attention
For osteoarthritis , NICE guidance (NG226) recommends a holistic approach: Education and self-management : Understanding the condition and strategies to manage symptoms Exercise and physical activity : Strengthening exercises, aerobic activity, and local muscle strengthening programmes Weight management : For those who are overweight or obese, structured weight loss programmes Pharmacological options : Topical NSAIDs as first-line
Davidson, C
NAC supplements may ease symptoms of mental health conditions such as depression, schizophrenia, and substance use disorders
In short: While B12 shots are FDA-approved for treating serious conditions such as anemia and malabsorption, they are also used in wellness settings to help people with subclinical deficiencies feel more focused and energized
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