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In contrast, the AIM-HIGH (Atherothrombosis intervention in metabolic syndrome with low HDL/high triglycerides: impact on global health outcomes) trial, which examined the incremental effect of extended-release nicotinic acid (1.5-2 g/day) on 3,414 patients who had established CVD and atherogenic dyslipidemia and were treated with simvastatin (+/- ezetimibe), provided disappointing results
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The statistical analysis was performed using XLStats 2017 software (Addinsoft, New York, NY)
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Liebelt EL, Balk SJ, Faber W, et al
Body weight reduction with tirzepatide by sex: a subgroup analysis of the SURMOUNT clinical trials
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