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Research protocols often use doses ranging from 500 to 1000 mcg, taken once or twice daily
Glucocorticoids chronic toxicity profile related to long-term use is problematic
For additional glycemic control: Increase dosage in 2.5 mg increments after at least 4 weeks on current dose
When given intraperitoneally (i.e., 10 g/kg b.w.), NaBPC157 was shown to prevent the development of alloxan as well as streptozotocin induced diabetes in rats
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Burwinkel B, Kreuder J, Schweitzer S, Vorgerd M, Gempel K, Gerbitz KD, Kilimann MW: Carnitine transporter OCTN2 mutations in systemic primary carnitine deficiency: a novel Arg169Gln mutation and a recurrent Arg282ter mutation associated with an unconventional splicing abnormality
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