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In the PIONEER- 4 trial, semaglutide was not less effective than liraglutide at lowering HbA1c at its daily oral formulation dose [97]
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In the trial that pitted Foundayo against dapagliflozin, the highest dose of Foundayo reduced blood sugar levels by up to 1.7 percentage points versus 0.8 points for dapagliflozin, with 7.3% weight loss versus 3.0% In the third trial, which tested Foundayo on top of insulin glargine, blood sugar levels dropped up to 2.1 points versus 0.8 points for placebo plus insulin, with 6.1% weight loss versus a slight gain
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