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Independent commentary in Aesthetic Medicine Magazine is consistent: the licensed Aqualyx product has a body of evidence, the unlicensed alternatives do not, and the regulator-warned products should be treated with caution
"GHK-Cu improved skin quality, stimulated hair growth, accelerated wound healing, and had antioxidant and anti-inflammatory effects." Pickart L., Margolina A
Available at: Gorgojo-Martnez JJ, Mezquita-Raya P, Carretero-Gmez J, et al
Conversely, treatment with GHK-Cu led to a significant reduction in this score (Figures 1D,E)
(7) Vladimir N Anisimov, Vladimir K H Khavinson, Mauro Provinciali, Irina N Alimova, et al (2002) Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice International Journal of Cancer, 2002 Sep 1, Volume 101 (Issue 1), Pages 7-10
Indeed, there are now several dual GIP/GLP-1 receptor agonists in clinical development, including tirzepatide, which was approved by the FDA and EMA for the treatment of type 2 diabetes in 2022
