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This usually resolves as the body adjusts

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If two drugs use the same pathway, they can cause a backup, leading to toxic levels of one drug or making another less effective

The above leads to the overproduction of ROS and RNS, and it intensifies cytokine and chemokine secretion via a positive feedback loop (174)

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doi:10.3389/fcell.2021.685522 [8] Wakeman M, Archer DT