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Additionally, the weight loss was superior compared with what adults achieved with semaglutide 2.4 mg alone (Wegovy, Novo Nordisk) or cagrilintide 2.4 mg alone (Novo Nordisk)

Therefore, the Food and Drug Administration (FDA) released a guidance requiring all new drugs for glycemic control in T2DM patients to demonstrate cardiovascular safety, a policy that was continued and further emphasized in the 2020 FDA Guidance for Diabetes Drug Development [7, 8]

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These models help scientists explore biological processes related to connective tissue biology, angiogenic signaling, and nitric oxide pathway regulation

All plasmid constructs were verified through DNA sequencing (Macrogen Europe, Amsterdam, the Netherlands)

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