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Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

Semaglutide is a GLP-1 agonist, Tirzepatide is a dual GLP-1 and GIP agonist, and Retatrutide is a triple GLP-1, GIP, and glucagon agonist

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Others struggle with impulsive eating, nighttime snacking, emotional eating, or rapid meal pacing that prevents them from recognizing fullness signals

Specifically, reduced GLP-1 was associated with altered expression of the pro-inflammatory macrophage marker CD86

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