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However, ideally in clinical practice, we hope to achieve at least 10-15% [bodyweight loss], which can lead to more meaningful metabolic health, says Glickman, a triple board certified family medicine, lifestyle medicine, and obesity medicine physician and the founder of Revolution Medicine

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For individuals with type 2 diabetes, blood glucose control may deteriorate as the medication's effects on increasing glucose-dependent insulin secretion and decreasing glucagon secretion wane

There is no MHRA-approved reconstitution protocol for this compound