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The unintended consequence was predictable

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a , Relative body weight change of C57BL6 mice in vehicle and combo treatment groups

p=0.01 and p=0.36

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2.2.2 Key driving factors 2.2.2.1 Iron overaccumulation The core driving factor of ferroptosis is the excessive accumulation of iron, and this process is mainly regulated by iron homeostasis regulators such as transferrin receptor (TFR), ferritin, and ferroportin (FPN) (Zhang et al., 2025c)