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The primary reason practitioners and their patients should be interested in using glutathione in IBS is that research suggests it is effective for helping maintain a normal inflammatory response in the gut, thus beneficially addressing IBD symptoms.* And in cases where the underlying mechanisms of the condition do overlap, a glutathione supplement could be just as beneficial in IBS as it is in IBD.* When glutathione facilitates antioxidant processes, it minimizes free radical exposure, which can trigger an inflammatory response imbalance.* If an imbalance in inflammatory response is involved in either IBS or IBD, then a glutathione supplement can be an appropriate choice.* Indeed, as far back as 1998, scientists have recognized that intestinal glutathione synthesis is impaired in patients with IBD, and this dysregulation might play a role in the etiology and progression of the condition