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DNA-hybrid-gated multifunctional mesoporous silica nanocarriers for dual-targeted and MicroRNA-responsive controlled drug delivery

Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism

Future research should aim to clarify the specific molecular pathways involved, establish dependable biomarkers for early detection, and investigate new therapeutic targets to enhance patient outcomes

The process works like this: intestinal microbiota convert levocarnitine to trimethylamine (TMA), which then travels to the liver where the enzyme FMO3 oxidizes it to TMAO

the nucleotide change resulted in an amino acid substitution in the protein

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