The Centers for Disease Control and Prevention (CDC) reports that approximately 3% of adults over age 50 will develop a serious B12 deficiency that can impair health
Sensitive individuals may start lower, but 1 mg remains the standard maintenance floor
class FIN such as Ras-selective lethal small molecule 3 (RSL3) (Figure 1): L-buthionine sulfoximine (BSO) suppresses glutamate-cycteine ligase (GCL) and induces GSH depletion ( Post-Translational Modifications of GPX4 in Cancer Cells Besides small molecular compounds like FINs, post-translational modifications (PTMs) also provide an emerging perspective to regulate its protein level/activity (Figure 2)
Mansour TE, Bueding E (1954) The actions of antimonials on glycolytic enzymes of Schistosoma mansoni
However, the major concern with BPC 157 is the lack of substantial evidence confirming its safety in humans
The material below is summarised strictly for research-use-only (RUO) context and is not medical advice, nor a dosing guide, nor a suggestion that either compound is safe or effective in people