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The Big Trial of a GLP-1 drug (Wegovy) to Reduce Major Cardiovascular Events Presented at the American Heart Association and simultaneously published in NEJM today is the trial of over 17,600 patients who were randomly assigned either the GLP-1 semaglutide (a glucagon-like peptide-1 receptor agonist) or placebo and were followed for well over 3 years
By focusing on Safety Mode and feeding your gut the right fibres, stabilising your blood sugar, meeting your protein needs, and respecting your need for rest, you are teaching your brain that it no longer needs to scream for survival
Weight loss and lifestyle changes have proven to be effective in restoring menstrual regularity and reproductive function, improving hyperandrogenism, glucose and lipid metabolism, and insulin sensitivity, thus reducing cardiovascular risk in women with PCOS [18,19,20]
This includes continued body composition monitoring, optional complementary therapies (NAD+, B12, lipotropics), and physician check-ins
A few are not, especially at high doses or through an IV
Endocrine Reviews, 26 (3), 346360
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