[1] These effects are typically dose-dependent, most pronounced during dose escalation, and tend to diminish over time
Primary Handling Editors: Yanina-Yasmin Pesch and Alfredo Gimenez-Cassina, in collaboration with the Nature Metabolism team
For some, this may cause flushing when drinking
Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
This chapter focuses on phase II biotransformation reactions (also called conjugation reactions) which generally serve as a detoxifying step in metabolism of drugs and other xenobiotics as well as endogenous substrates
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