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It's also ubiquitous

They peak around week 20 of the protocol, which corresponds to the early weeks on the maximum 2.4mg dose

Viruses 5 , 439469 (2013)

[5] previously evaluated the separate roles of insulin and IGF-1 in directly regulating GH secretion, using the Cre/loxP system to knock down the insulin receptor (INSR) and IGF-1 receptor (IGFIR) in primary mouse pituitary cell cultures