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In addition to its metabolic effects, GLP-1 acts centrally to maintain energy balance by activating glucagon-like peptide-1 receptors (GLP-1Rs) located in key regions of the brain

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Some less common side effects worth discussing include anxiety , insomnia , sleep disruption , and dizziness

Magnesium is a natural muscle relaxant that also draws water into the intestines

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Kawai T, Sun B, Yoshino H, Feng D, Suzuki Y, Fukazawa M, Nagao S, Wainscott DB, Showalter AD, Droz BA, Kobilka TS, Coghlan MP, Willard FS, Kawabe Y, Kobilka BK, & Sloop KW, Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist, Proc