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placebo group, but many patients withdrew from the study

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Similarly, the STEP UP Obesity trial revealed that about 33% of patients on the 7.2 mg dose lost 25% or more of their starting weight, while only 15% of those on the lower dose achieved the same level of weight loss

It can inhibit the activation of PI3K/AKT signaling through the inverse regulation of IGF-1 expression and ultimately suppress the tumorigenesis of cervical cancer cells (80)