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It produces roughly 250350 mL per day

* Percent Daily Reference Intakes (RI) are based on a 2,000 calorie diet

The 12:6 split reflects the typical relative quantities used when the two classes are studied together, with the GHRH-class compound as the larger fraction

USA 110 , 88828887 (2013)

This allows the host to mount protective immunity when needed while limiting excessive inflammation and maintaining tolerance to commensals