In 2021, the GBD study estimated that 529 million people [95% uncertainty interval (UI) 500-564 million] were living with diabetes worldwide [3]
This markedly increased its half-life in the body, making it more suitable for clinical use than human GLP-1
Evans, G
Saroglitazar, a PPAR-/ agonist, at a dosage of 4 mg qd significantly improved ALT, liver fat content (LFC), insulin resistance, and atherogenic dyslipidemia in patients with MASLD/MASH (NCT03061721)
Acknowledgements We would like to express our sincere gratitude to Professor Zhentao Zhang from the Department of Neurology at Renmin Hospital, Wuhan University, for his invaluable guidance and support throughout this research
In TRIUMPH-4, the 12 mg group lost an average of 71.2 pounds over 68 weeks