The first GLP-1 agonist, exenatide (Byetta), approved in 2005, required twice-daily injections [13]
New clinical trials have opened doors for these medications beyond just weight management and diabetes treatment
But the indirect costs are worse
3.6.3 Uncertainty management and the clinical pathway Beyond aggregate effects, the Bayesian framework offers a more intuitive representation of the potential range of individual response through posterior predictive distributions, effectively transforming heterogeneity from a statistical artifact into a tool for managing clinical uncertainty
Look at how it behaves under load, how much it sags, how much heat it builds, how balanced the cells are, and whether internal resistance has risen noticeably over time.
How should my practice handle patient transitions if medication sources change