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Whether cycling is necessary from a safety perspective remains unknown
NNMT (nicotinamide N-methyltransferase) is an enzyme that methylates nicotinamide, draining methyl donors and reducing NAD+ salvage
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The standard schedule is a starting point, not a strict rule The 2024 NICE guideline NG239 on B12 deficiency in over 16s makes an important point: the optimal route, dose and frequency of B12 replacement have never been firmly established, and have often followed custom and historical practice
September 24, 2021
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