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I posted a poll on Twitter that asked learners/users you would replace vitamin B 12 in a patient with pernicious anemia, focusing on the choice between intramuscular (IM) and oral (PO) routes

For patients seeking weight loss who request B12 injections, GPs should: Assess for genuine deficiency through appropriate blood tests rather than empirical treatment Provide education about the lack of evidence supporting B12 for weight loss in non-deficient individuals Explore underlying concerns about weight and energy levels, addressing these through appropriate channels Signpost to evidence-based resources such as NHS weight management services according to local pathways Patients should contact their GP if they experience unexplained fatigue, neurological symptoms (numbness, tingling, balance problems), or signs of anaemia (pallor, breathlessness, palpitations), as these may indicate B12 deficiency requiring investigation

Clinical trials tested doses up to 1mg daily without significant adverse effects, but this does not mean higher doses produce better results or that exceeding researched doses is safe

However, this varies depending on weight, metabolism, and food intake

It was designed to be a therapeutic agent for neurodegenerative diseases due to its potential to facilitate synaptogenesis, the formation of new synapses between neurons

This Vitamin B-12 shot can be used at home as an injection, under instruction of a doctor