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Some individuals may require weekly injections initially, followed by maintenance doses at longer intervals

Check vitamin B12 levels in people treated with metformin who have symptoms suggestive of vitamin B12 deficiency This will also include patients found to have megaloblastic anaemia (raised mean corpuscular volume [MVC]), who may be asymptomatic (MHRA, 2022)

Additional experimental observations have explored interactions with mitochondrial function, oxidative stressrelated pathways, and stem cell signaling networks

People with ME/CFS may be at risk of vitamin B12 deficiency if they have a diet that is low in vitamin B12-containing foods especially meat, dairy and fish

The second part of how AOD9604 works is just as important

Many of the foods commonly eaten every day can make this worse as they increase intestinal permeability, also called leaky gut