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While researchers found that GLP-1 drugs collectively showed positive impact on managing type 2 diabetes by effectively lowering haemoglobin A1c and fasting plasma glucose levels, higher doses of these drugs were shown to significantly increase adverse gastrointestinal reactions
Tirzepatides, such as Mounjaro and Zepbound, are technically classified differently because they incorporate agonists of both GLP-1 and another hormone called glucose-dependent insulinotropic polypeptide (GIP)