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Effects of Drugs on Skin Conditions Cutaneous Drug Reactions (CDRs) occur when drugs cause changes in skin coloration ranging from yellowish discoloration and purple spots on light skinned people (called purpura) to black patches on dark-skinned individuals (called hyperpigmentation)
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There was a significant difference in IGF-BP-3 between Group 2 and Group 1&3 ( p 0.05)
Last year (2025), Novo Nordisk had sought to further position itself in the obesity drug market with a bid to acquire Metsera, a New York-based clinical-stage bio/pharmaceutical company focused on obesity and cardiometabolic diseases, eventually losing a bidding war with Pfizer, which acquired Metsera last November (November 2025) in a deal worth up to $11 billion
[9] Intrinsic toxicity is typically dose-dependent and frequently detected within hours to days after toxicant exposure
Future research should also explore tirzepatides effects across different OSAS severities and phenotypes, paving the way for personalized therapeutic strategies
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