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Cell lines were classified as highly sensitive (hits) if they demonstrated a log 2 (fold change) 0.5 in at least one of the top three concentration tiers (0.5, 1 or 2 M)
R., DeYoung, M
In fact, up to 15 percent of people have two copies of this mutation
These findings agree with genome-wide screening outcomes and further highlight the potential importance of NK effector function for in vivo telomerase inhibitor efficacy
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