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A 2022 paper in Aging characterised that epitalon protected against post-ovulatory aging-related damage of mouse oocytes in vitro (PMID 35413689), framing one route by which the compound engages reproductive-aging research

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Anton-Sanchez L, Larraaga P, Benavides-Piccione R, Fernaud-Espinosa I, DeFelipe J, Bielza C (2017) Three-dimensional spatial modeling of spines along dendritic networks in human cortical pyramidal neurons

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Furthermore, WB analysis was conducted on extracts from the aortas of aging mice, showing consistent results with in vitro experiments: increased expression of p-P53 and decreased expression of total P53 after FOXO4-DRI treatment

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