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Results During a median follow-up of 7.26 years, the incidence rate of ESRD was 2.03 per 1,000 person-years

The drug has rapid pharmacokinetics with intravenous administration, an onset of action within 12 minutes, and a short half-life of approximately 2 minutes, leading to increases in systolic blood pressure (1020 mmHg) and heart rate (515 bpm)

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A subsequent study to understand the mechanism of action of DHS was carried out employing CHO cells as a cellular model (Table 2) [65]

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