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Sources: TRIUMPH-1 (Lilly topline, May 2026), SURMOUNT-1 (Jastreboff NEJM 2022, DXA: Tobias DOM 2025), STEP 1 (Wilding NEJM 2021, DXA exploratory), ATTAIN-1 (Lilly/NEJM 2025), Phase 2 T2D DXA (Coskun, Lancet Diab Endo 2025)

Gradual titration allows your body to adjust comfortably, and we can provide strategies to manage symptoms if they occur." Key Insight: Open and honest communication about potential side effects, their duration, and management strategies helps patients feel informed, reassured, and more confident in following the treatment plan

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The study found that regular marijuana use was associated with decreased frontal white matter integrity and was regulated by the fatty acid amide hydrolase genotype

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