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[See Dosage and Administration (2.2).] Hepatic Insufficiency In patients with moderate hepatic insufficiency (Child-Pugh score 7 to 9), mean AUC and Cmax of sitagliptin increased approximately 21% and 13%, respectively, compared to healthy matched controls following administration of a single 100 mg dose of Januvia

In the skin, collagen provides structure, elasticity, and hydration, which are essential for maintaining a youthful appearance

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