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To understand the nature of X(PC)s off-target cleavage activity more deeply, we began by investigating cleavage of downstream caspase-1 substrates and observed that X(PC) likely cleaved IL-1 (Fig

MC1R activation on immune cells engages anti-inflammatory pathways

14 Some research suggests that certain types of fiber (fermentable fibers found in oats, beans, and some fruits/vegetables) can be broken down by gut bacteria into short-chain fatty acids, which may naturally stimulate the body's own GLP-1 production

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