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To view or add a comment, sign in How to individualize renoprotective therapy in obese patients with chronic kidney disease: a commentary by the Diabesity Working Group of the ERA Open Access Nephrology Dialysis Transplantation, Volume 40, Issue 10, October 2025, Pages 19771988, Published: 13 May 2025 The interrelated pandemics of obesity and type 2 diabetes mellitus (T2DM) are fuelling an increase in the prevalence of chronic kidney disease (CKD), which amplifies the risk of cardiovascular events and may progress to end-stage kidney disease (ESKD)
Because retatrutide remains investigational and is not yet approved for clinical use, these observations come from controlled trial conditions and may not reflect outcomes in broader clinical practice
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Current studies have revealed a strong link between ferroptosis and the GSH system, which has become a hotspot in the field of CVDs
The average weight loss achieved in the Semaglutide FDA study for weight loss was almost 15% of the initial body weight but it is not unusual to see a patient lose 20% of their body weight over the course of the treatment
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