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Indirect effects An indirect pathway for GLP-1RAs to mediate risk for PDAC is via acute or chronic pancreatitis, which are risk factors for PDAC 24,25

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That being said, neither study specifically states how much one must take of vitamin B12 (or folate) for their blood serum levels to register as either "very high" or "extremely high." For that reason, although vitamin B12 (and folate) supplementation are important during pregnancy, it's best to look to your healthcare provider for guidance

Medical management is often of limited success

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What are the considerations for intravenous B12 dosing