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The main rationale for cycling rather than continuous use involves conservative safety practices given limited long-term human data, cost management, and theoretical concerns about receptor desensitization with extended exposure

2 Folate supplementation can correct these haematological effects of B12 deficiency but not the neurological complications, which include neuropathies, such as tingling and numbness in the arms and legs, sensory and motor disturbances, including abnormal gait, and cognitive changes

A vitamin B12 deficiency can affect oral health and cause the These symptoms occur due to a reduction in RBC production, which results in less oxygen reaching the tongue

In studies on aged skin, it tightened loose skin and improved elasticity