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However, the results may be influenced by external factors including inflammation, growth factors and organ dysfunctions ( via organ biopsies or imaging methods as biomagnetic susceptometry or magnetic resonance imaging (MRI) although these methods are rarely applied due to their invasiveness, costs or insufficient validation ( Using this variety of methods, over the years several characteristics of an altered iron metabolism in MDS and AML patients have been found together indicating a state of iron overload in these diseases ( Figure 2B )

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This process leads to vascular wall thickening and lumen narrowing, thereby promoting pulmonary vascular remodeling and the progression of pulmonary hypertension (177, 178)

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The experimental peptide BPC-157 is prohibited under the World Anti-Doping Agency (WADA) Prohibited List in the category of S0 Unapproved Substances