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No adrenaline (epinephrine), not prednisolone, is the first-line emergency treatment for anaphylaxis, as recommended by the Resuscitation Council UK and NICE NG183
Likewise, multiple large clinical studies with various GLP-1 RAs have shown a more favorable trend in lipid profiles with GLP-1 RAs, although these were not evaluated as the primary outcomes (Table 2)
refer to the NHS medicines information pages and the MHRA/EMC SmPC for eligibility and safety details [13] Semaglutide (Wegovy) approved by the MHRA and recommended by NICE (Technology Appraisal TA875) for weight management in eligible adults (BMI 35 kg/m with at least one weight-related comorbidity, or BMI 3034
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