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It also regulates matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), ensuring controlled tissue remodeling and balanced extracellular matrix turnover[1]
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Methionine is an essential amino acid involved in lipid metabolism, inositol participates in cellular signaling, and choline supports hepatic lipid export
showed that in cultured rat ventricular myocytes, trimetazidines beneficial effects were only observed when cells were undergoing hypoxia and not during normoxia, highlighting trimetazidine as a metabolic regulator that would not increase mitochondrial function in healthy states [123]
R Hurrell, I Egli
